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KMID : 1038120230560050658
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Clinical Endoscopy
2023 Volume.56 No. 5 p.658 ~ p.665
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Anesthesia care provider sedation versus conscious sedation for endoscopic ultrasound?guided tissue acquisition: a retrospective cohort study
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Sneha Shaha
Yinglin Gao
Jiahao Peng
Kendrick Che
John J. Kim
Wasseem Skef
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Abstract
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Background/Aims : We aimed to study the effects of sedation on endoscopic ultrasound?guided tissue acquisition.
Methods : We conducted a retrospective study evaluating the role of sedation in endoscopic ultrasound?guided tissue acquisition by comparing two groups: anesthesia care provider (ACP) sedation and endoscopist-directed conscious sedation (CS).
Results : Technical success was achieved in 219/233 (94.0%) in the ACP group and 114/136 (83.8%) in the CS group (p=0.0086). In multivariate analysis, the difference in technical success between the two groups was not significant (adjusted odds ratio [aOR], 0.5; 95% confidence interval [CI], 0.234?1.069; p=0.0738). A successful diagnostic yield was present in 146/196 (74.5%) in the ACP group and 66/106 (62.3%) in the CS group, respectively (p=0.0274). In multivariate analysis, the difference in diagnostic yield between the two groups was not significant (aOR, 0.643; 95% CI, 0.356?1.159; p=0.142). A total of 33 adverse events (AEs) were observed. The incidence of AEs was significantly lower in the CS group (5/33 CS vs. 28/33 ACP; OR, 0.281; 95% CI, 0.095?0.833; p=0.022).
Conclusions : CS provided equivalent technical success and diagnostic yield for malignancy in endoscopic ultrasound?guided tissue acquisition. Increased AEs were associated with anesthesia for the endoscopic ultrasound?guided tissue acquisition.
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KEYWORD
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Anesthesia, Conscious sedation, Endoscopic ultrasound?guided fine needle aspiration, General anesthesia, Pancreatic neoplasm
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